Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175.

Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175.

A phase I randomised, controlled, single blind, dose escalation trial was conducted to evaluate safety and immunogenicity of JAIVAC-1, a recombinant blood stage vaccine candidate against Plasmodium falciparum malaria, composed of a physical mixture of two recombinant proteins, PfMSP-1(19), the 19 kD...

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Bibliographic Details
Main Authors: Chetan E Chitnis, Paushali Mukherjee, Shantanu Mehta, Syed Shams Yazdani, Shikha Dhawan, Ahmad Rushdi Shakri, Rukmini Bhardwaj, Puneet Kumar Gupta, Dhiraj Hans, Suman Mazumdar, Bijender Singh, Sanjeev Kumar, Gaurav Pandey, Varsha Parulekar, Nathalie Imbault, Preethi Shivyogi, Girish Godbole, Krishna Mohan, Odile Leroy, Kavita Singh, Virander S Chauhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4415778?pdf=render

Internet

http://europepmc.org/articles/PMC4415778?pdf=render

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