Of numbers and movement – understanding transcription factor pathogenesis by advanced microscopy

Of numbers and movement – understanding transcription factor pathogenesis by advanced microscopy

Transcription factors (TFs) are life-sustaining and, therefore, the subject of intensive research. By regulating gene expression, TFs control a plethora of developmental and physiological processes, and their abnormal function commonly leads to various developmental defects and diseases in humans. N...

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Bibliographic Details
Main Authors: Julia M. T. Auer, Jack J. Stoddart, Ioannis Christodoulou, Ana Lima, Kassiani Skouloudaki, Hildegard N. Hall, Vladana Vukojević, Dimitrios K. Papadopoulos
Format: Article
Language:English
Published: The Company of Biologists 2020-12-01
Series:Disease Models & Mechanisms
Subjects:
haploinsufficiency
quantitative microscopy
transcription factors
super-resolution microscopy
transcriptional regulation
Online Access:http://dmm.biologists.org/content/13/12/dmm046516

Internet

http://dmm.biologists.org/content/13/12/dmm046516

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