Compartmental Analysis to Predict the Biodistribution of [166Ho]- DOTA-Bevacizumab for Targeted Radiotherapy Purpose

Compartmental Analysis to Predict the Biodistribution of [166Ho]- DOTA-Bevacizumab for Targeted Radiotherapy Purpose

Purpose- The main aim of this study was to develop the pharmacokinetic model for the colorectal cancer’s complex 166Ho-DOTA-Bevacizumab in normal and tumoral rats to analyze of behavior as a new composition for diagnosing and treatment. The use of compartmental analysis allows a mathematical separa...

Full description

Bibliographic Details
Main Authors: Alireza Khorrami Moghaddam, Amir Hakimi, Alireza Mardanshahi, Amir R. Jalilian, Hossein Amirfakhrian, Hossein Mousavi Anijdan
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-09-01
Series:Frontiers in Biomedical Technologies
Subjects:
Compartment analysis
166Ho-Avastin
Biodistribution modeling
Radio targeted therapy
Internal dosimetery.
Online Access:https://fbt.tums.ac.ir/index.php/fbt/article/view/55

Internet

https://fbt.tums.ac.ir/index.php/fbt/article/view/55

Similar Items