Atrazine Causes Autophagy- and Apoptosis-Related Neurodegenerative Effects in Dopaminergic Neurons in the Rat Nigrostriatal Dopaminergic System

Atrazine Causes Autophagy- and Apoptosis-Related Neurodegenerative Effects in Dopaminergic Neurons in the Rat Nigrostriatal Dopaminergic System

Atrazine (2-chloro-4-ethytlamino-6-isopropylamine-1,3,5-triazine; ATR) is widely used as a broad-spectrum herbicide. Animal studies have demonstrated that ATR exposure can cause cell death in dopaminergic neurons. The molecular mechanisms underlying ATR-induced neuronal cell death, however, are unkn...

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Bibliographic Details
Main Authors: Xiao-Yao Song, Jia-Nan Li, Yan-Ping Wu, Bo Zhang, Bai-Xiang Li
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:International Journal of Molecular Sciences
Subjects:
atrazine
autophagy
apoptosis
neurotoxicity
wistar rats
dopaminergic neuron
Online Access:http://www.mdpi.com/1422-0067/16/6/13490

Internet

http://www.mdpi.com/1422-0067/16/6/13490

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