Heterogeneity in tertiary lymphoid structure B-cells correlates with patient survival in metastatic melanoma

Background Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral tissues that may support adaptive immune responses. Their presence has been associated with clinical response to checkpoint blockade therapy (CBT), but it is unknown whether TLS have prognostic significance independen...

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Bibliographic Details
Main Authors: Ileana S Mauldin, Nolan A Wages, Max O Meneveau, Kevin T Lynch, Samuel J Young, Craig L Slingluff Jr, Victor H Engelhard
Format: Article
Language:English
Published: BMJ Publishing Group 2021-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/6/e002273.full