Leucine and protein metabolism in obese Zucker rats.

Branched-chain amino acids (BCAAs) are circulating nutrient signals for protein accretion, however, they increase in obesity and elevations appear to be prognostic of diabetes. To understand the mechanisms whereby obesity affects BCAAs and protein metabolism, we employed metabolomics and measured ra...

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Bibliographic Details
Main Authors: Pengxiang She, Kristine C Olson, Yoshihiro Kadota, Ayami Inukai, Yoshiharu Shimomura, Charles L Hoppel, Sean H Adams, Yasuko Kawamata, Hideki Matsumoto, Ryosei Sakai, Charles H Lang, Christopher J Lynch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3603883?pdf=render