Potential Importance of Early Focal Radiotherapy Following Gross Total Resection for Long-Term Survival in Children With Embryonal Tumors With Multilayered Rosettes

Potential Importance of Early Focal Radiotherapy Following Gross Total Resection for Long-Term Survival in Children With Embryonal Tumors With Multilayered Rosettes

Embryonal tumor with multilayered rosettes (ETMR) is a rare, aggressive embryonal central nervous system tumor characterized by LIN28A expression and alterations in the C19MC locus. ETMRs predominantly occur in young children, have a dismal prognosis, and no definitive treatment guidelines have been...

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Bibliographic Details
Main Authors: Lisa Mayr, Johannes Gojo, Andreas Peyrl, Amedeo A. Azizi, Natalia M. Stepien, Thomas Pletschko, Thomas Czech, Christian Dorfer, Sander Lambo, Karin Dieckmann, Christine Haberler, Marcel Kool, Irene Slavc
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
embryonal tumor with multilayered rosette
embryonal tumor with abundant neuropil and true rosette
radiotherapy
focal radiotherapy
intrathecal therapy
embryonal brain tumors
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.584681/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.584681/full

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