Candida albicans scavenges host zinc via Pra1 during endothelial invasion.

The ability of pathogenic microorganisms to assimilate essential nutrients from their hosts is critical for pathogenesis. Here we report endothelial zinc sequestration by the major human fungal pathogen, Candida albicans. We hypothesised that, analogous to siderophore-mediated iron acquisition, C. a...

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Bibliographic Details
Main Authors: Francesco Citiulo, Ilse D Jacobsen, Pedro Miramón, Lydia Schild, Sascha Brunke, Peter Zipfel, Matthias Brock, Bernhard Hube, Duncan Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22761575/?tool=EBI