Identification of intima-to-media signals for flow-induced vascular remodeling using correlative gene expression analysis

Abstract Changes in blood flow can induce arterial remodeling. Intimal cells sense flow and send signals to the media to initiate remodeling. However, the nature of such intima-media signaling is not fully understood. To identify potential signals, New Zealand white rabbits underwent bilateral carot...

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Bibliographic Details
Main Authors: John Kolega, Kerry E. Poppenberg, Hee-Woong Lim, Liza C. Gutierrez, Sricharan S. Veeturi, Adnan H. Siddiqui, Hamidreza Rajabzadeh-Oghaz, Vincent M. Tutino
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95403-x