Droplet Digital PCR Based Androgen Receptor Variant 7 (AR-V7) Detection from Prostate Cancer Patient Blood Biopsies

Droplet Digital PCR Based Androgen Receptor Variant 7 (AR-V7) Detection from Prostate Cancer Patient Blood Biopsies

Androgen receptor splice variant V7 (AR-V7) was recently identified as a valuable predictive biomarker in metastatic castrate-resistant prostate cancer. Here, we report a new, sensitive and accurate screen for AR-V7 mRNA expression directly from circulating tumor cells (CTCs): We combined EpCAM-base...

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Bibliographic Details
Main Authors: Yafeng Ma, Alison Luk, Francis P. Young, David Lynch, Wei Chua, Bavanthi Balakrishnar, Paul de Souza, Therese M. Becker
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
biomarker
androgen receptor
AR-V7
prostate cancer
ddPCR
CTC
Online Access:http://www.mdpi.com/1422-0067/17/8/1264

Internet

http://www.mdpi.com/1422-0067/17/8/1264

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