AMPK Mediates Muscle Mass Change But Not the Transition of Myosin Heavy Chain Isoforms during Unloading and Reloading of Skeletal Muscles in Mice

AMPK Mediates Muscle Mass Change But Not the Transition of Myosin Heavy Chain Isoforms during Unloading and Reloading of Skeletal Muscles in Mice

5′AMP-activated protein kinase (AMPK) plays an important role in the regulation of skeletal muscle mass and fiber-type distribution. However, it is unclear whether AMPK is involved in muscle mass change or transition of myosin heavy chain (MyHC) isoforms in response to unloading or increas...

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Bibliographic Details
Main Authors: Tatsuro Egawa, Yoshitaka Ohno, Ayumi Goto, Shingo Yokoyama, Tatsuya Hayashi, Katsumasa Goto
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
atrophy
regrowth
sirtuin 1 (SIRT1)
peroxisome proliferator-activated receptor gamma coactivator 1-α (PGC1α)
heat shock protein
fiber-type
Online Access:http://www.mdpi.com/1422-0067/19/10/2954

Internet

http://www.mdpi.com/1422-0067/19/10/2954

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