Establishment of an Endoscopy-Guided Minimally Invasive Orthotopic Mouse Model of Colorectal Cancer

Open orthotopic mouse models of colorectal cancer have disadvantages such as the requirement for advanced surgical skills or the trauma caused by laparotomy. To overcome these drawbacks, this study aimed to evaluate the establishment of a minimally invasive model using murine colonoscopy. CT26 and M...

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Bibliographic Details
Main Authors: Chen Chen, Jens Neumann, Florian Kühn, Serene M. L. Lee, Moritz Drefs, Joachim Andrassy, Jens Werner, Alexandr V. Bazhin, Tobias S. Schiergens
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/10/3007