Digital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients

Digital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients

Abstract Patients requiring diagnostic testing for coronavirus disease 2019 (COVID-19) are routinely assessed by reverse-transcription quantitative polymerase chain reaction (RT-qPCR) amplification of Sars-CoV-2 virus RNA extracted from oro/nasopharyngeal swabs. Despite the good specificity of the a...

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Bibliographic Details
Main Authors: Paolo Poggio, Paola Songia, Chiara Vavassori, Veronica Ricci, Cristina Banfi, Silvia Stella Barbieri, Gloria Garoffolo, Veronika A. Myasoedova, Luca Piacentini, Angela Raucci, Alessandro Scopece, Elena Sommariva, Maria Cristina Vinci, Davide Carcione, Maria Luisa Biondi, Maria Elisabetta Mancini, Alberto Formenti, Daniele Andreini, Emilio M. Assanelli, Piergiuseppe Agostoni, Marina Camera, Gualtiero I. Colombo, Maurizio Pesce
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83723-x

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https://doi.org/10.1038/s41598-021-83723-x

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