Rooperol tetraacetate decreases cytokine mRNA levels and binding capacity of transcription factors in U937 cells

We have previously described inhibition of the synthesis of three acute-phase inflammatory cytokines in human and rat macrophages by acetate esters of rooperol, a dicatechol of plant origin. Analysing the mechanism of anticytokine activity of rooperol, we compared levels of TNF α , IL-1 β and IL-6 m...

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Bibliographic Details
Main Authors: A. Guzdek, H. Rokita, J. Cichy, A. C. Allison, A. Koj
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/09629359891324