Role of the Bone Microenvironment in the Development of Painful Complications of Skeletal Metastases

Cancer-induced bone pain (CIBP) is the most common and painful complication in patients with bone metastases. It causes a significant reduction in patient quality of life. Available analgesic treatments for CIBP, such as opioids that target the central nervous system, come with severe side effects a...

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Bibliographic Details
Main Authors: Sun H. Park, Matthew R. Eber, D. Brooke Widner, Yusuke Shiozawa
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/5/141