A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration

A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration

Abstract We conducted a genome-wide association study (GWAS) on the outcome of anti-VEGF treatment for exudative age-related macular degeneration (AMD) in a prospective cohort. Four hundred and sixty-one treatment-naïve AMD patients were recruited at 13 clinical centers and all patients were treated...

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Main Authors: Kenji Yamashiro, Keisuke Mori, Shigeru Honda, Mariko Kano, Yasuo Yanagi, Akira Obana, Yoichi Sakurada, Taku Sato, Yoshimi Nagai, Taiichi Hikichi, Yasushi Kataoka, Chikako Hara, Yasurou Koyama, Hideki Koizumi, Munemitsu Yoshikawa, Masahiro Miyake, Isao Nakata, Takashi Tsuchihashi, Kuniko Horie-Inoue, Wataru Matsumiya, Masashi Ogasawara, Ryo Obata, Seigo Yoneyama, Hidetaka Matsumoto, Masayuki Ohnaka, Hirokuni Kitamei, Kaori Sayanagi, Sotaro Ooto, Hiroshi Tamura, Akio Oishi, Sho Kabasawa, Kazuhiro Ueyama, Akiko Miki, Naoshi Kondo, Hiroaki Bessho, Masaaki Saito, Hidenori Takahashi, Xue Tan, Keiko Azuma, Wataru Kikushima, Ryo Mukai, Akihiro Ohira, Fumi Gomi, Kazunori Miyata, Kanji Takahashi, Shoji Kishi, Hiroyuki Iijima, Tetsuju Sekiryu, Tomohiro Iida, Takuya Awata, Satoshi Inoue, Ryo Yamada, Fumihiko Matsuda, Akitaka Tsujikawa, Akira Negi, Shin Yoneya, Takeshi Iwata, Nagahisa Yoshimura
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09632-0

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https://doi.org/10.1038/s41598-017-09632-0

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