A deterministic method for estimating free energy genetic network landscapes with applications to cell commitment and reprogramming paths

Depicting developmental processes as movements in free energy genetic landscapes is an illustrative tool. However, exploring such landscapes to obtain quantitative or even qualitative predictions is hampered by the lack of free energy functions corresponding to the biochemical Michaelis–Menten or Hi...

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Bibliographic Details
Main Authors: Victor Olariu, Erica Manesso, Carsten Peterson
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.160765