Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies.

Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies.

A fundamental challenge for developing an effective and safe HIV-1 vaccine is to identify vaccine immunogens that can initiate and maintain immune responses leading to elicitation of broadly neutralizing HIV-1 antibodies (bnAbs) through complex maturation pathways. We have previously found that HIV-...

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Bibliographic Details
Main Authors: Zheng Yang, Jingjing Li, Qingsheng Liu, Tingting Yuan, Yanyu Zhang, Li-Qing Chen, Qi Lou, Zehua Sun, Huazhong Ying, Jianqing Xu, Dimiter S Dimitrov, Mei-Yun Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126428

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https://doi.org/10.1371/journal.pone.0126428

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