Morphine Addiction and Oxidative Stress: The Potential Effects of Thioredoxin-1

Long-term administration of morphine for the management of chronic pain will result in tolerance to its analgesic effect and could even cause drug dependence. Numerous studies have demonstrated significant redox alteration in morphine dependence and addiction. Thioredoxin-1 (Trx-1) play important ro...

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Bibliographic Details
Main Authors: Xian-Si Zeng, Wen-Shuo Geng, Zhan-Qi Wang, Jin-Jing Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
CPP
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00082/full