Control of human gene expression: High abundance of divergent transcription in genes containing both INR and BRE elements in the core promoter.

BACKGROUND:DNA sequence elements in the core promoter can play a central role in regulation of gene expression. Core elements (e.g. INR and TATA box) are located within ~50bp of the transcription start site and both upstream and downstream elements are known. Although all can affect the level of gen...

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Bibliographic Details
Main Author: Jay C Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6107252?pdf=render