Genetic engineering strategies to prevent the effects of antibody and complement on xenogeneic chondrocytes
Advances in animal transgenesis may allow using xenogeneic chondrocytes in tissue-engineering applications for clinical cartilage repair. Porcine cartilage is rejected by humoral and cellular mechanisms that could be overcome by identifying key molecules triggering rejection and developing effective...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AO Research Institute Davos
2015-11-01
|
| Series: | European Cells & Materials |
| Subjects: | |
| Online Access: | http://www.ecmjournal.org/papers/vol030/pdf/v030a18.pdf |