Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation.

Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation.

Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that has a heterogeneous population composed of a pool of strains with distinct characteristics, including variable levels of virulence. In previous work, transcriptome analyses of parasite genes after infection of human foreskin fi...

Full description

Bibliographic Details
Main Authors: Antonio Edson R Oliveira, Milton C A Pereira, Ashton T Belew, Ludmila R P Ferreira, Larissa M N Pereira, Eula G A Neves, Maria do Carmo P Nunes, Barbara A Burleigh, Walderez O Dutra, Najib M El-Sayed, Ricardo T Gazzinelli, Santuza M R Teixeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008781

Internet

https://doi.org/10.1371/journal.ppat.1008781

Similar Items