Influence of light–dark cycle on delayed recovery from isoflurane anesthesia induced by hypnotics in mice

Influence of light–dark cycle on delayed recovery from isoflurane anesthesia induced by hypnotics in mice

We previously reported that brotizolam, but not suvorexant, delayed recovery from isoflurane anesthesia in mice. However, the effects of hypnotics may be altered by the circadian rhythm. Locomotor activity was measured using sighted (ICR and C57BL/6J) and blind (FVB/N and C3H/HeN) mice, and the effe...

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Bibliographic Details
Main Authors: Atsunobu Sugano, Hiroki Murai, Syunpei Horiguchi, Yuma Yoshimoto, Yuki Amano, Tomoki Kimura, Yoshinori Iba
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Pharmacological Sciences
Subjects:
Hypnotics
Circadian rhythm
Chronopharmacology
Orexinergic neurons
GABAergic neurons
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000141

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http://www.sciencedirect.com/science/article/pii/S1347861321000141

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