Prion Protein Protects against Renal Ischemia/Reperfusion Injury.

Prion Protein Protects against Renal Ischemia/Reperfusion Injury.

The cellular prion protein (PrPC), a protein most noted for its link to prion diseases, has been found to play a protective role in ischemic brain injury. To investigate the role of PrPC in the kidney, an organ highly prone to ischemia/reperfusion (IR) injury, we examined wild-type (WT) and PrPC kno...

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Bibliographic Details
Main Authors: Bo Zhang, Daniel Cowden, Fan Zhang, Jue Yuan, Sandra Siedlak, Mai Abouelsaad, Liang Zeng, Xuefeng Zhou, John O'Toole, Alvin S Das, Diane Kofskey, Miriam Warren, Zehua Bian, Yuqi Cui, Tao Tan, Adam Kresak, Robert E Wyza, Robert B Petersen, Gong-Xian Wang, Qingzhong Kong, Xinglong Wang, John Sedor, Xiongwei Zhu, Hua Zhu, Wen-Quan Zou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4556704?pdf=render

Internet

http://europepmc.org/articles/PMC4556704?pdf=render

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