Longitudinal Plasma Measures of Trimethylamine N‐Oxide and Risk of Atherosclerotic Cardiovascular Disease Events in Community‐Based Older Adults

Longitudinal Plasma Measures of Trimethylamine N‐Oxide and Risk of Atherosclerotic Cardiovascular Disease Events in Community‐Based Older Adults

Background Trimethylamine N‐oxide (TMAO) is a gut microbiota‐dependent metabolite of dietary choline, L‐carnitine, and phosphatidylcholine‐rich foods. On the basis of experimental studies and patients with prevalent disease, elevated plasma TMAO may increase risk of atherosclerotic cardiovascular di...

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Bibliographic Details
Main Authors: Yujin Lee, Ina Nemet, Zeneng Wang, Heidi T. M. Lai, Marcia C. de Oliveira Otto, Rozenn N. Lemaitre, Amanda M. Fretts, Nona Sotoodehnia, Matthew Budoff, Joseph A. DiDonato, Barbara McKnight, W. H. Wilson Tang, Bruce M. Psaty, David S. Siscovick, Stanley L. Hazen, Dariush Mozaffarian
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
animal food
atherosclerotic cardiovascular disease
renal function
trimethylamine N‐oxide
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.020646

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https://www.ahajournals.org/doi/10.1161/JAHA.120.020646

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