Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease

Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease

Background/Aims: In the present study, we examined whether DNA methylation of the brain-derived neurotrophic factor (BDNF) promoter is associated with the manifestation and clinical presentation of Alzheimer's disease (AD). Methods: Of 20 patients with AD and 20 age-matched normal controls (NCs...

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Bibliographic Details
Main Authors: Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayama
Format: Article
Language:English
Published: Karger Publishers 2015-03-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
Epigenetics
Brain-derived neurotrophic factor
Alzheimerߣs disease
BDNF
DNA methylation
Neurotrophic factors
Online Access:http://www.karger.com/Article/FullText/375367

Internet

http://www.karger.com/Article/FullText/375367

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