A Versatile Bioreactor for Dynamic Suspension Cell Culture. Application to the Culture of Cancer Cell Spheroids.

A versatile bioreactor suitable for dynamic suspension cell culture under tunable shear stress conditions has been developed and preliminarily tested culturing cancer cell spheroids. By adopting simple technological solutions and avoiding rotating components, the bioreactor exploits the laminar hydr...

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Bibliographic Details
Main Authors: Diana Massai, Giuseppe Isu, Denise Madeddu, Giulia Cerino, Angela Falco, Caterina Frati, Diego Gallo, Marco A Deriu, Giuseppe Falvo D'Urso Labate, Federico Quaini, Alberto Audenino, Umberto Morbiducci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4856383?pdf=render