Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention.

Hemorrhagic fever viruses, including the filoviruses (Ebola and Marburg) and arenaviruses (Lassa and Junín viruses), are serious human pathogens for which there are currently no FDA approved therapeutics or vaccines. Importantly, transmission of these viruses, and specifically late steps of budding,...

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Bibliographic Details
Main Authors: Ziying Han, Jonathan J Madara, Andrew Herbert, Laura I Prugar, Gordon Ruthel, Jianhong Lu, Yuliang Liu, Wenbo Liu, Xiaohong Liu, Jay E Wrobel, Allen B Reitz, John M Dye, Ronald N Harty, Bruce D Freedman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4634230?pdf=render