Inhibition of Sophocarpine on poly I:C/ D-GalN induced immunological liver injury in mice

Inhibition of Sophocarpine on poly I:C/ D-GalN induced immunological liver injury in mice

Increasing evidence has suggested that natural killer (NK) cells contribute to the pathogenesis of human immunological liver injury. Previous studies have demonstrated that Sophocarpine exerts activity in immune modulation. It also has a therapeutic effect on liver protection in that it can alleviat...

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Bibliographic Details
Main Authors: Yinqiu Huang, Pengyan Li, Jiabo Wang, Houqin Zhou, Zhirui Yang, Ruichuang Yang, Zhaofang Bai, Lifu Wang, Jianyu Li, Honghong Liu, Yanling Zhao, Xiaohe Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pharmacology
Subjects:
Sophocarpine
NK cell activity
Immunological liver injury
NKG2D-DAP12
Poly I: C/ D-GalN
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00256/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00256/full

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