The X-ray repair cross complementing protein 1 (XRCC1) rs25487 polymorphism and susceptibility to cirrhosis in Brazilian patients with chronic viral hepatitis

Introduction. The progression of hepatic disease in chronic viral hepatitis is accompanied by an increased production of reactive oxygen species (ROS), as well as an accumulation of oxidative DNA damage, which is primarily repaired through base excision repair. XRCC1 (X-ray repair cross complementin...

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Main Authors: Samantha Therezinha Almeida Pereira Leite, Nathália Marques-Guimarães, Júlio César Silva-Oliveira, Francisco José Dutra-Souto, Raquel Alves-dos-Santos, Carmen Lucia Bassi-Branco
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119313146