Investigation of association between PFO complicated by cryptogenic stroke and a common variant of the cardiac transcription factor GATA4.

Patent foramen ovale (PFO) is associated with clinical conditions including cryptogenic stroke, migraine and varicose veins. Data from studies in humans and mouse suggest that PFO and the secundum form of atrial septal defect (ASDII) exist in an anatomical continuum of septal dysmorphogenesis with a...

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Bibliographic Details
Main Authors: Mahdi Moradi Marjaneh, Edwin P Kirk, Maximilian G Posch, Cemil Ozcelik, Felix Berger, Roland Hetzer, Robyn Otway, Tanya L Butler, Gillian M Blue, Lyn R Griffiths, Diane Fatkin, Jeremy J Martinson, David S Winlaw, Michael P Feneley, Richard P Harvey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108965?pdf=render