Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization

Macrophage activation and polarization are closely linked with metabolic rewiring, which is required to sustain their biological functions. These metabolic alterations allow the macrophages to adapt to the microenvironment changes associated with inflammation or tissue damage (hypoxia, nutrient imba...

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Bibliographic Details
Main Authors: Paula Díaz-Bulnes, María Laura Saiz, Carlos López-Larrea, Ramón M. Rodríguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
UPR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02951/full