Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig.

Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig.

Genetically modified pigs have become a popular model system in fundamental research, agricultural and biomedical applications. However, random integration often result in unstable expression of transgene and unpredictable phenotypes. The Rosa26 locus has been widely used to produce genetic modified...

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Bibliographic Details
Main Authors: Qingran Kong, Tang Hai, Jing Ma, Tianqing Huang, Dandan Jiang, Bingteng Xie, Meiling Wu, Jiaqiang Wang, Yuran Song, Ying Wang, Yilong He, Jialu Sun, Kui Hu, Runfa Guo, Liu Wang, Qi Zhou, Yanshuang Mu, Zhonghua Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169413?pdf=render

Internet

http://europepmc.org/articles/PMC4169413?pdf=render

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