Alterations in the Gut Microbiome and Cecal Metabolome During Klebsiella pneumoniae-Induced Pneumosepsis

Alterations in the Gut Microbiome and Cecal Metabolome During Klebsiella pneumoniae-Induced Pneumosepsis

Klebsiella (K.) pneumoniae is a common cause of pneumonia-derived sepsis in human and is associated with high morbidity and mortality. The microbiota promotes and maintains host immune homeostasis during bacterial infections. However, the mechanisms by which the gut microbiota affects immune respons...

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Bibliographic Details
Main Authors: Ting Wu, Fangming Xu, Cong Su, Hongru Li, Na Lv, Yanyan Liu, Yufeng Gao, Yanhu Lan, Jiabin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
K. pneumoniae pneumonia
metabolome
gut microbiome
multi-omics analyses
short-chain fatty acids
phagocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01331/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01331/full

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