p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling

Abstract Background The adult mammary epithelium is composed of basal and luminal cells. The luminal lineage comprises two major cell populations, positive and negative for estrogen and progesterone receptors (ER and PR, respectively), both containing clonogenic progenitor cells. Deregulated ER/PR−...

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Bibliographic Details
Main Authors: Aurélie Chiche, Amandine Di-Cicco, Laura Sesma-Sanz, Laura Bresson, Pierre de la Grange, Marina A. Glukhova, Marisa M. Faraldo, Marie-Ange Deugnier
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Breast Cancer Research
Subjects:
Mammary gland
Breast cancer
Stem cells
p53
Met
Online Access:http://link.springer.com/article/10.1186/s13058-019-1101-8

Internet

http://link.springer.com/article/10.1186/s13058-019-1101-8

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