Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer

Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer

Androgen receptor (AR)-mediated signaling is essential for the growth and differentiation of the normal prostate and is the primary target for androgen deprivation therapy in prostate cancer. Tat interactive protein 60 kDa (Tip60) is a histone acetyltransferase that is critical for AR activation. It...

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Bibliographic Details
Main Authors: Kah Ni Tan, Vicky M. Avery, Catalina Carrasco-Pozo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
androgen receptor
Tip60
prostate cancer
metabolism
c-Myc
HIF-1α
Online Access:https://www.mdpi.com/1422-0067/21/18/6622

Internet

https://www.mdpi.com/1422-0067/21/18/6622

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