PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro

PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease and its pathogenesis remains unclear. Fibroblast-like synoviocytes (FLSs) play an important role in the pathogenesis of RA. Proline-serine-threonine phosphatase interacting protein 2 (PSTPIP2) is an adaptor protein, which is asso...

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Bibliographic Details
Main Authors: Yao Yao, Haixia Yu, Yaru Liu, Qingqing Xu, Xiaofeng Li, Xiaoming Meng, Cheng Huang, Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
PSTPIP2
FLSs
inflammatory response
proliferation
NF-κB signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01432/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01432/full

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