Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids

Identification of gene targets is one of the major challenges to construct superior microbial cell factory for chemical synthesis. Here, the authors employ CRISPRi and omics analyses for genome-scale target genes identification for high-titer production of free fatty acids in E. coli.

Bibliographic Details
Main Authors: Lixia Fang, Jie Fan, Shulei Luo, Yaru Chen, Congya Wang, Yingxiu Cao, Hao Song
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25243-w