DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures

DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures

Mutations and copy number variants affecting DYRK1A gene encoding the dual-specificity tyrosine phosphorylation-regulated kinase 1A are among the most frequent genetic causes of neurodevelopmental disorders including autism spectrum disorder (ASD) associated with microcephaly, febrile seizures and s...

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Bibliographic Details
Main Authors: Matthieu Raveau, Atsushi Shimohata, Kenji Amano, Hiroyuki Miyamoto, Kazuhiro Yamakawa
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Neurobiology of Disease
Subjects:
DYRK1A
Cognitive flexibility
Autism
Sociability deficit
Communication deficit
Febrile seizure
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302814

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http://www.sciencedirect.com/science/article/pii/S0969996117302814

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