Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct–Ligated MouseSummary

Background & Aims: Inflammation plays an important role in the pathogenesis of cholestatic liver injury, but it is unclear whether the inflammasome is involved and is the objective of this study. Methods: Gene expression was analyzed in the livers of patients with primary biliary cholangitis (n ...

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Bibliographic Details
Main Authors: Shi-Ying Cai, Maoxu Ge, Albert Mennone, Rafaz Hoque, Xinshou Ouyang, James L. Boyer
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19301845