E2 regulates epigenetic signature on Neuroglobin enhancer-promoter in neuronal cells

E2 regulates epigenetic signature on Neuroglobin enhancer-promoter in neuronal cells

Estrogens are neuroprotective factors in several neurological diseases. Neuroglobin (NGB) is one of the estrogen target gene involved in neuroprotection, but little is known about its transcriptional regulation. Estrogen genomic pathway in gene expression regulation is mediated by estrogen receptors...

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Bibliographic Details
Main Authors: Michela eGuglielmotto, Stefania eReineri, Andrea eIannello, Giulio eFerrero, Ludovica eVanzan, Valentina eMiano, Laura eRicci, Elena eTamagno, Michele eDe Bortoli, Santina eCutrupi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Epigenetic regulation
estrogen receptor
Neuroglobin
chromatin remodelling
Genomic regions
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00147/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00147/full

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