Effect of Shikonin on Spinal Cord Injury in Rats Via Regulation of HMGB1/TLR4/NF-kB Signaling Pathway

Effect of Shikonin on Spinal Cord Injury in Rats Via Regulation of HMGB1/TLR4/NF-kB Signaling Pathway

Background/Aims: Shikonin, a compound extracted from Zicao, has been demonstrated to hold anti-bacterial, anti-inflammatory, and anti-tumor activities in various diseases and it has been shown to protect human organs from injuries. However, the effect of shikonin on the recovery of spinal cord injur...

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Bibliographic Details
Main Authors: Yihui Bi, Yapeng Zhu, Mingkai Zhang, Keke Zhang, Xingyi Hua, Zheng Fang, Jian Zhou, Wenjie Dai, Yixing Cui, Jun Li, Tao You
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Shikonin
SCI
Inflammation response
Apoptosis
HMGB1/TLR4/NF-κB signaling pathway
Online Access:http://www.karger.com/Article/FullText/480474

Internet

http://www.karger.com/Article/FullText/480474

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