The role of PI3K-mediated AMPA receptor changes in post-conditioning of propofol in brain protection

The role of PI3K-mediated AMPA receptor changes in post-conditioning of propofol in brain protection

Abstract Background We aimed to study the role of amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor (AMPAR) glutamate receptor 2 (GluR2) subunit trafficking, and activity changes in short-term neuroprotection provided by propofol post-conditioning. We also aimed to determine the role of ph...

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Bibliographic Details
Main Authors: Chenxu Wang, Ying Wei, Yuan Yuan, Yonghao Yu, Keliang Xie, Beibei Dong, Yuan Shi, Guolin Wang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Neuroscience
Subjects:
Propofol
Post-conditioning
Phosphoinositide-3-kinase (PI3K)
Amino-3-hydroxy- 5-methylisoxazole-4-propionic acid receptor (AMPAR)
Ischemia–reperfusion injury
Rat
Online Access:http://link.springer.com/article/10.1186/s12868-019-0532-6

Internet

http://link.springer.com/article/10.1186/s12868-019-0532-6

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