Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.

Phenotypic drug discovery requires billions of cells for high-throughput screening (HTS) campaigns. Because up to several million different small molecules will be tested in a single HTS campaign, even small variability within the cell populations for screening could easily invalidate an entire camp...

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Bibliographic Details
Main Authors: Peter Reinhardt, Michael Glatza, Kathrin Hemmer, Yaroslav Tsytsyura, Cora S Thiel, Susanne Höing, Sören Moritz, Juan A Parga, Lydia Wagner, Jan M Bruder, Guangming Wu, Benjamin Schmid, Albrecht Röpke, Jürgen Klingauf, Jens C Schwamborn, Thomas Gasser, Hans R Schöler, Jared Sterneckert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3606479?pdf=render

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