Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins
F-box proteins (FBPs) are substrate-recruiting subunits of Skp1-cullin1-FBP (SCF)-type E3 ubiquitin ligases. To date, 69 FBPs have been identified in humans, but ubiquitinated substrates have only been identified for a few, with the majority of FBPs remaining ‘orphans’. In recent years, a growing bo...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2013-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130131 |