PRIC295, a Nuclear Receptor Coactivator, Identified from PPAR𝛼-Interacting Cofactor Complex
The peroxisome proliferator-activated receptor-𝛼 (PPAR𝛼) plays a key role in lipid metabolism and energy combustion. Chronic activation of PPAR𝛼 in rodents leads to the development of hepatocellular carcinomas. The ability of PPAR𝛼 to induce expression of its target genes depends on Mediator, an evo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2010-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2010/173907 |