Evogliptin Suppresses Calcific Aortic Valve Disease by Attenuating Inflammation, Fibrosis, and Calcification

Evogliptin Suppresses Calcific Aortic Valve Disease by Attenuating Inflammation, Fibrosis, and Calcification

Calcific aortic valve disease (CAVD) accompanies inflammatory cell infiltration, fibrosis, and ultimately calcification of the valve leaflets. We previously demonstrated that dipeptidyl peptidase-4 (DPP-4) is responsible for the progression of aortic valvular calcification in CAVD animal models. As...

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Bibliographic Details
Main Authors: Bongkun Choi, Eun-Young Kim, Ji-Eun Kim, Soyoon Oh, Si-On Park, Sang-Min Kim, Hyuksu Choi, Jae-Kwan Song, Eun-Ju Chang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
calcific aortic valve disease
dipeptidyl peptidase-4
aortic valve
inflammation
fibrosis
calcification
Online Access:https://www.mdpi.com/2073-4409/10/1/57

Internet

https://www.mdpi.com/2073-4409/10/1/57

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