Polyfunctional Nitriles in Organic Syntheses: A Novel Route to Aminopyrroles, Pyridazines and Pyrazolo[3,4-c]pyridazines

Phenacylmalononitrile 1 reacts with dimethylformamide dimethyl acetal to yield an enaminone which could be readily converted into a pyrrole or an aminopyridazine by treating with ammonium acetate and hydrazine hydrate, respectively. Compound 1 reacted with hydrazine hydrate in ethanol at room temper...

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Bibliographic Details
Main Authors: Mohamed Hilmy Elnagdi, Heinz Kolshorn, Herbert Meier, Saleh M. Al-Mousawi, Moustafa Sherief Moustafa
Format: Article
Language:English
Published: MDPI AG 2009-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/2/798/