Serum amyloid A1 mediates myotube atrophy via Toll‐like receptors

Serum amyloid A1 mediates myotube atrophy via Toll‐like receptors

Abstract Background Critically ill patients frequently develop muscle atrophy and weakness in the intensive‐care‐unit setting [intensive care unit‐acquired weakness (ICUAW)]. Sepsis, systemic inflammation, and acute‐phase response are major risk factors. We reported earlier that the acute‐phase prot...

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Bibliographic Details
Main Authors: Alexander Hahn, Melanie Kny, Cristina Pablo‐Tortola, Mihail Todiras, Michael Willenbrock, Sibylle Schmidt, Katrin Schmoeckel, Ilka Jorde, Marcel Nowak, Ernst Jarosch, Thomas Sommer, Barbara M. Bröker, Stephan B. Felix, Claus Scheidereit, Steffen Weber‐Carstens, Christian Butter, Friedrich C. Luft, Jens Fielitz
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Sepsis
NF‐κB
CLP
Muscle atrophy
ICUAW
Online Access:https://doi.org/10.1002/jcsm.12491

Internet

https://doi.org/10.1002/jcsm.12491

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