Effective Pro-Inflammatory Induced Activity of GALT, a Conserved Antigen in A. Pleuropneumoniae, Improves the Cytokines Secretion of Macrophage via p38, ERK1/2 and JNK MAPKs Signal Pathway

Effective Pro-Inflammatory Induced Activity of GALT, a Conserved Antigen in A. Pleuropneumoniae, Improves the Cytokines Secretion of Macrophage via p38, ERK1/2 and JNK MAPKs Signal Pathway

GALT is a highly conserved antigen in gram-negative bacteria, and has been shown to play a crucial role in the pathogenesis of many zoonoses. Actinobacillus pleuropneumoniae (APP) is a widespread respiratory system pathogen belonging to the Pasteuriaceae family. The functional mechanisms of GALT in...

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Bibliographic Details
Main Authors: Fei Zhang, Qin Zhao, Jin Tian, Yung-Fu Chang, Xintian Wen, Xiaobo Huang, Rui Wu, Yiping Wen, Qigui Yan, Yong Huang, Xiaoping Ma, Xinfeng Han, Chang Miao, Sanjie Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Actinobacillus pleuropneumoniae
pro-inflammatory cytokines
MAPKs pathway
innate immune system
toll-like receptors
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00337/full

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https://www.frontiersin.org/article/10.3389/fcimb.2018.00337/full

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